| Holyoke to Punta Gorda (Florida) | 1,184.31 mi (1,905.96 km) |
| Holyoke to Puyallup (Washington) | 2,420.91 mi (3,896.07 km) |
| Holyoke to Queen Creek (Arizona) | 2,197.14 mi (3,535.95 km) |
| Holyoke to Queens (New York) | 117.46 mi (189.03 km) |
| Holyoke to Quincy (Illinois) | 986.60 mi (1,587.79 km) |
| Holyoke to Quincy (Massachusetts) | 83.04 mi (133.64 km) |
| Holyoke to Raceland (Louisiana) | 1,320.36 mi (2,124.91 km) |
| Holyoke to Racine (Wisconsin) | 773.04 mi (1,244.09 km) |
| Holyoke to Radcliff (Kentucky) | 765.10 mi (1,231.31 km) |
| Holyoke to Radford (Virginia) | 548.19 mi (882.23 km) |
| Holyoke to Rahway (New Jersey) | 139.68 mi (224.80 km) |
| Holyoke to Raleigh (North Carolina) | 545.67 mi (878.18 km) |
| Holyoke to Ramona (California) | 2,472.53 mi (3,979.15 km) |
| Holyoke to Ramsey (Minnesota) | 1,056.78 mi (1,700.73 km) |
| Holyoke to Ramsey (New Jersey) | 111.26 mi (179.06 km) |
