| Holyoke to Oxford (Alabama) | 933.15 mi (1,501.75 km) |
| Holyoke to Oxford (Mississippi) | 1,061.75 mi (1,708.72 km) |
| Holyoke to Oxford (Ohio) | 658.88 mi (1,060.37 km) |
| Holyoke to Oxnard (California) | 2,554.06 mi (4,110.37 km) |
| Holyoke to Oxon Hill (Maryland) | 328.18 mi (528.16 km) |
| Holyoke to Ozark (Alabama) | 1,032.16 mi (1,661.09 km) |
| Holyoke to Ozark (Missouri) | 1,148.50 mi (1,848.33 km) |
| Holyoke to Pace (Florida) | 1,134.40 mi (1,825.64 km) |
| Holyoke to Pacific Grove (California) | 2,622.13 mi (4,219.91 km) |
| Holyoke to Pacifica (California) | 2,622.61 mi (4,220.68 km) |
| Holyoke to Paducah (Kentucky) | 920.72 mi (1,481.75 km) |
| Holyoke to Pahrump (Nevada) | 2,331.81 mi (3,752.68 km) |
| Holyoke to Painesville (Ohio) | 443.54 mi (713.80 km) |
| Holyoke to Palatine (Illinois) | 787.73 mi (1,267.72 km) |
| Holyoke to Palatka (Florida) | 1,002.92 mi (1,614.04 km) |
