| Holyhead to Indianola (Iowa) | 3,968.39 mi (6,386.50 km) |
| Holyhead to Indio (California) | 5,167.38 mi (8,316.09 km) |
| Holyhead to Inglewood (California) | 5,223.82 mi (8,406.93 km) |
| Holyhead to Inkster (Michigan) | 3,538.91 mi (5,695.32 km) |
| Holyhead to Inver Grove Heights (Minnesota) | 3,784.02 mi (6,089.79 km) |
| Holyhead to Inwood (New York) | 3,238.03 mi (5,211.11 km) |
| Holyhead to Iona (Florida) | 4,257.67 mi (6,852.05 km) |
| Holyhead to Ionia (Michigan) | 3,574.82 mi (5,753.11 km) |
| Holyhead to Iowa City (Iowa) | 3,879.07 mi (6,242.76 km) |
| Holyhead to Irmo (South Carolina) | 3,843.57 mi (6,185.64 km) |
| Holyhead to Irondale (Alabama) | 4,089.77 mi (6,581.85 km) |
| Holyhead to Ironton (Ohio) | 3,688.97 mi (5,936.83 km) |
| Holyhead to Irvine (California) | 5,221.20 mi (8,402.70 km) |
| Holyhead to Irving (Texas) | 4,526.03 mi (7,283.94 km) |
| Holyhead to Isabela (Puerto Rico) | 4,067.27 mi (6,545.63 km) |
