| Holyhead to El Sobrante (California) | 5,199.93 mi (8,368.48 km) |
| Holyhead to Eldersburg (Maryland) | 3,421.26 mi (5,505.98 km) |
| Holyhead to Elfers (Florida) | 4,201.35 mi (6,761.42 km) |
| Holyhead to Elgin (Illinois) | 3,741.14 mi (6,020.78 km) |
| Holyhead to Elizabeth (New Jersey) | 3,253.74 mi (5,236.39 km) |
| Holyhead to Elizabeth City (North Carolina) | 3,537.41 mi (5,692.91 km) |
| Holyhead to Elizabethton (Tennessee) | 3,776.51 mi (6,077.71 km) |
| Holyhead to Elizabethtown (Kentucky) | 3,854.08 mi (6,202.55 km) |
| Holyhead to Elizabethtown (Pennsylvania) | 3,372.99 mi (5,428.31 km) |
| Holyhead to Elk City (Oklahoma) | 4,486.72 mi (7,220.67 km) |
| Holyhead to Elk Grove (California) | 5,063.83 mi (8,149.44 km) |
| Holyhead to Elk Grove Village (Illinois) | 3,730.15 mi (6,003.09 km) |
| Holyhead to Elk Plain (Washington) | 4,600.63 mi (7,403.99 km) |
| Holyhead to Elk River (Minnesota) | 3,778.27 mi (6,080.53 km) |
| Holyhead to Elkhart (Indiana) | 3,667.96 mi (5,903.02 km) |
