| Holyhead to Dumas (Texas) | 4,554.84 mi (7,330.30 km) |
| Holyhead to Dumont (New Jersey) | 3,233.36 mi (5,203.59 km) |
| Holyhead to Duncan (Oklahoma) | 4,474.44 mi (7,200.91 km) |
| Holyhead to Duncanville (Texas) | 4,534.91 mi (7,298.24 km) |
| Holyhead to Dundalk (Maryland) | 3,409.04 mi (5,486.32 km) |
| Holyhead to Dunedin (Florida) | 4,213.22 mi (6,780.53 km) |
| Holyhead to Dunkirk (New York) | 3,376.36 mi (5,433.73 km) |
| Holyhead to Dunmore (Pennsylvania) | 3,276.94 mi (5,273.73 km) |
| Holyhead to Dunwoody (Georgia) | 3,976.47 mi (6,399.51 km) |
| Holyhead to Durango (Colorado) | 4,689.85 mi (7,547.58 km) |
| Holyhead to Durant (Oklahoma) | 4,445.01 mi (7,153.56 km) |
| Holyhead to Durham (North Carolina) | 3,660.13 mi (5,890.41 km) |
| Holyhead to Dyer (Indiana) | 3,735.81 mi (6,012.20 km) |
| Holyhead to Dyersburg (Tennessee) | 4,071.59 mi (6,552.59 km) |
| Holyhead to Eagan (Minnesota) | 3,788.11 mi (6,096.38 km) |
