| Holyhead to Desert Hot Springs (California) | 5,165.09 mi (8,312.42 km) |
| Holyhead to DeSoto (Texas) | 4,535.47 mi (7,299.14 km) |
| Holyhead to Destin (Florida) | 4,241.43 mi (6,825.93 km) |
| Holyhead to Destrehan (Louisiana) | 4,419.28 mi (7,112.14 km) |
| Holyhead to Detroit (Michigan) | 3,526.66 mi (5,675.60 km) |
| Holyhead to Diamond Bar (California) | 5,204.26 mi (8,375.44 km) |
| Holyhead to Diamond Springs (California) | 5,031.55 mi (8,097.51 km) |
| Holyhead to Dickinson (North Dakota) | 4,018.86 mi (6,467.73 km) |
| Holyhead to Dickinson (Texas) | 4,630.50 mi (7,452.06 km) |
| Holyhead to Dickson (Tennessee) | 3,992.36 mi (6,425.08 km) |
| Holyhead to Difficult Run (Virginia) | 3,460.13 mi (5,568.55 km) |
| Holyhead to Dinuba (California) | 5,109.79 mi (8,223.41 km) |
| Holyhead to Discovery Bay (California) | 5,099.59 mi (8,207.00 km) |
| Holyhead to Dix Hills (New York) | 3,213.40 mi (5,171.47 km) |
| Holyhead to Dixon (California) | 5,075.32 mi (8,167.93 km) |
