| Holyhead to Delhi (California) | 5,101.85 mi (8,210.64 km) |
| Holyhead to Delray Beach (Florida) | 4,184.12 mi (6,733.69 km) |
| Holyhead to Deltona (Florida) | 4,104.42 mi (6,605.43 km) |
| Holyhead to Deming (New Mexico) | 4,956.62 mi (7,976.91 km) |
| Holyhead to Denison (Texas) | 4,463.96 mi (7,184.06 km) |
| Holyhead to Dent (Ohio) | 3,735.31 mi (6,011.41 km) |
| Holyhead to Denton (Texas) | 4,513.83 mi (7,264.31 km) |
| Holyhead to Dentsville (South Carolina) | 3,835.16 mi (6,172.10 km) |
| Holyhead to Denver (Colorado) | 4,453.48 mi (7,167.19 km) |
| Holyhead to Depew (New York) | 3,332.76 mi (5,363.56 km) |
| Holyhead to Derby (Connecticut) | 3,180.13 mi (5,117.93 km) |
| Holyhead to Derby (Kansas) | 4,294.36 mi (6,911.10 km) |
| Holyhead to Des Moines (Iowa) | 3,959.84 mi (6,372.75 km) |
| Holyhead to Des Moines (Washington) | 4,579.57 mi (7,370.10 km) |
| Holyhead to Des Plaines (Illinois) | 3,725.39 mi (5,995.44 km) |
