| Holyhead to Ansonia (Connecticut) | 3,178.77 mi (5,115.74 km) |
| Holyhead to Antelope (California) | 5,045.97 mi (8,120.70 km) |
| Holyhead to Anthem (Arizona) | 5,021.92 mi (8,082.00 km) |
| Holyhead to Antioch (California) | 5,101.38 mi (8,209.87 km) |
| Holyhead to Antioch (Illinois) | 3,711.24 mi (5,972.67 km) |
| Holyhead to Apache Junction (Arizona) | 5,027.25 mi (8,090.58 km) |
| Holyhead to Apex (North Carolina) | 3,671.27 mi (5,908.33 km) |
| Holyhead to Apollo Beach (Florida) | 4,211.41 mi (6,777.60 km) |
| Holyhead to Apopka (Florida) | 4,127.78 mi (6,643.02 km) |
| Holyhead to Apple Valley (California) | 5,154.13 mi (8,294.77 km) |
| Holyhead to Apple Valley (Minnesota) | 3,792.79 mi (6,103.90 km) |
| Holyhead to Appleton (Wisconsin) | 3,639.45 mi (5,857.13 km) |
| Holyhead to Arbutus (Maryland) | 3,418.23 mi (5,501.11 km) |
| Holyhead to Arcadia (California) | 5,203.76 mi (8,374.64 km) |
| Holyhead to Arcata (California) | 5,001.88 mi (8,049.75 km) |
