| Holyhead to Stonehaven | 270.00 mi (434.53 km) |
| Holyhead to Stourbridge | 119.14 mi (191.74 km) |
| Holyhead to Stowmarket | 247.87 mi (398.91 km) |
| Holyhead to Stranraer | 111.22 mi (178.99 km) |
| Holyhead to Stratford | 230.06 mi (370.25 km) |
| Holyhead to Stratford-upon-Avon | 144.65 mi (232.79 km) |
| Holyhead to Stratton Saint Margaret | 169.65 mi (273.03 km) |
| Holyhead to Streatham | 230.33 mi (370.69 km) |
| Holyhead to Street | 170.97 mi (275.15 km) |
| Holyhead to Streetly | 125.12 mi (201.37 km) |
| Holyhead to Stretford | 96.27 mi (154.93 km) |
| Holyhead to Strood | 253.00 mi (407.16 km) |
| Holyhead to Stroud | 148.39 mi (238.81 km) |
| Holyhead to Sudbury | 218.40 mi (351.48 km) |
| Holyhead to Sudbury | 240.99 mi (387.83 km) |
