| Holyhead to Shenfield | 238.48 mi (383.80 km) |
| Holyhead to Shenley Brook End | 184.41 mi (296.78 km) |
| Holyhead to Shenley Church End | 183.99 mi (296.11 km) |
| Holyhead to Shepperton | 220.39 mi (354.69 km) |
| Holyhead to Shepshed | 143.54 mi (231.01 km) |
| Holyhead to Shepton Mallet | 170.77 mi (274.83 km) |
| Holyhead to Sherborne | 186.23 mi (299.72 km) |
| Holyhead to Shevington | 82.00 mi (131.97 km) |
| Holyhead to Shildon | 151.73 mi (244.19 km) |
| Holyhead to Shipley | 122.64 mi (197.36 km) |
| Holyhead to Shirebrook | 141.25 mi (227.33 km) |
| Holyhead to Shiremoor | 173.91 mi (279.87 km) |
| Holyhead to Shirley | 234.64 mi (377.62 km) |
| Holyhead to Shoeburyness | 259.61 mi (417.81 km) |
| Holyhead to Shoreham-by-Sea | 251.97 mi (405.51 km) |
