| Cities | Distance |
|---|---|
| Holyhead to Scartho | 187.58 mi (301.88 km) |
| Holyhead to Scunthorpe | 164.95 mi (265.46 km) |
| Holyhead to Seacombe | 66.50 mi (107.02 km) |
| Holyhead to Seacroft | 134.94 mi (217.16 km) |
| Holyhead to Seaford | 266.80 mi (429.38 km) |
| Holyhead to Seaham | 170.30 mi (274.06 km) |
| Holyhead to Sedgley | 117.27 mi (188.73 km) |
| Holyhead to Selby | 149.85 mi (241.16 km) |
| Holyhead to Selsey | 241.45 mi (388.57 km) |
| Holyhead to Selston | 138.95 mi (223.62 km) |
| Holyhead to Sevenoaks | 247.27 mi (397.95 km) |
| Holyhead to Shanklin | 236.25 mi (380.21 km) |
| Holyhead to Sheerness | 261.45 mi (420.76 km) |
| Holyhead to Sheffield | 130.54 mi (210.08 km) |
| Holyhead to Sheldon | 133.43 mi (214.74 km) |