| Holyhead to Eckington | 134.93 mi (217.15 km) |
| Holyhead to Edgware | 217.50 mi (350.03 km) |
| Holyhead to Edinburgh | 191.60 mi (308.35 km) |
| Holyhead to Edmonton | 224.83 mi (361.83 km) |
| Holyhead to Egg Buckland | 202.17 mi (325.36 km) |
| Holyhead to Elgin | 304.33 mi (489.77 km) |
| Holyhead to Elland | 117.66 mi (189.36 km) |
| Holyhead to Ellesmere Port | 71.72 mi (115.42 km) |
| Holyhead to Ellon | 297.59 mi (478.93 km) |
| Holyhead to Eltham | 235.56 mi (379.10 km) |
| Holyhead to Ely | 213.67 mi (343.86 km) |
| Holyhead to Emsworth | 231.26 mi (372.17 km) |
| Holyhead to Enfield | 223.09 mi (359.03 km) |
| Holyhead to Enfield Lock | 224.47 mi (361.25 km) |
| Holyhead to Englefield Green | 214.96 mi (345.95 km) |
