| Holtsville to University Place (Washington) | 2,456.75 mi (3,953.76 km) |
| Holtsville to Upland (California) | 2,462.99 mi (3,963.80 km) |
| Holtsville to Upper Arlington (Ohio) | 529.86 mi (852.72 km) |
| Holtsville to Upper Grand Lagoon (Florida) | 1,022.99 mi (1,646.34 km) |
| Holtsville to Upper Montclair (New Jersey) | 60.47 mi (97.32 km) |
| Holtsville to Urbana (Illinois) | 797.04 mi (1,282.71 km) |
| Holtsville to Urbana (Maryland) | 249.29 mi (401.19 km) |
| Holtsville to Urbana (Ohio) | 564.73 mi (908.85 km) |
| Holtsville to Urbandale (Iowa) | 1,076.52 mi (1,732.48 km) |
| Holtsville to Utica (New York) | 193.54 mi (311.47 km) |
| Holtsville to Uvalde (Texas) | 1,702.18 mi (2,739.39 km) |
| Holtsville to Vacaville (California) | 2,576.58 mi (4,146.60 km) |
| Holtsville to Vadnais Heights (Minnesota) | 1,051.70 mi (1,692.55 km) |
| Holtsville to Vail (Arizona) | 2,161.31 mi (3,478.29 km) |
| Holtsville to Valdosta (Georgia) | 894.43 mi (1,439.45 km) |
