| Holtsville to Storm Lake (Iowa) | 1,145.90 mi (1,844.15 km) |
| Holtsville to Storrs (Connecticut) | 80.19 mi (129.05 km) |
| Holtsville to Stoughton (Wisconsin) | 843.70 mi (1,357.80 km) |
| Holtsville to Stow (Ohio) | 438.07 mi (705.01 km) |
| Holtsville to Streamwood (Illinois) | 787.51 mi (1,267.37 km) |
| Holtsville to Streator (Illinois) | 822.66 mi (1,323.95 km) |
| Holtsville to Streetsboro (Ohio) | 433.52 mi (697.69 km) |
| Holtsville to Strongsville (Ohio) | 458.85 mi (738.45 km) |
| Holtsville to Stuart (Florida) | 1,026.26 mi (1,651.61 km) |
| Holtsville to Stuarts Draft (Virginia) | 373.38 mi (600.90 km) |
| Holtsville to Sturgis (Michigan) | 645.27 mi (1,038.46 km) |
| Holtsville to Suamico (Wisconsin) | 805.59 mi (1,296.48 km) |
| Holtsville to Sudley (Virginia) | 274.54 mi (441.83 km) |
| Holtsville to Suffern (New York) | 60.93 mi (98.06 km) |
| Holtsville to Suffolk (Virginia) | 344.08 mi (553.74 km) |
