| Holtsville to St. Simons (Georgia) | 811.86 mi (1,306.56 km) |
| Holtsville to Stafford (Texas) | 1,481.00 mi (2,383.44 km) |
| Holtsville to Stallings (North Carolina) | 571.74 mi (920.13 km) |
| Holtsville to Stamford (Connecticut) | 33.53 mi (53.96 km) |
| Holtsville to Stanford (California) | 2,609.15 mi (4,199.02 km) |
| Holtsville to Stanton (California) | 2,489.44 mi (4,006.37 km) |
| Holtsville to Star (Idaho) | 2,205.25 mi (3,549.01 km) |
| Holtsville to Starkville (Mississippi) | 1,004.68 mi (1,616.88 km) |
| Holtsville to State College (Pennsylvania) | 251.65 mi (404.99 km) |
| Holtsville to Staten Island (New York) | 60.00 mi (96.56 km) |
| Holtsville to Statesboro (Georgia) | 753.61 mi (1,212.82 km) |
| Holtsville to Statesville (North Carolina) | 548.06 mi (882.01 km) |
| Holtsville to Staunton (Virginia) | 369.37 mi (594.45 km) |
| Holtsville to Steamboat Springs (Colorado) | 1,759.96 mi (2,832.39 km) |
| Holtsville to Steiner Ranch (Texas) | 1,564.15 mi (2,517.25 km) |
