| Holtsville to Smyrna (Delaware) | 171.44 mi (275.91 km) |
| Holtsville to Smyrna (Georgia) | 791.12 mi (1,273.18 km) |
| Holtsville to Smyrna (Tennessee) | 801.99 mi (1,290.67 km) |
| Holtsville to Snellville (Georgia) | 769.31 mi (1,238.09 km) |
| Holtsville to Snoqualmie (Washington) | 2,421.13 mi (3,896.43 km) |
| Holtsville to Snyder (Texas) | 1,632.42 mi (2,627.12 km) |
| Holtsville to Socastee (South Carolina) | 591.22 mi (951.48 km) |
| Holtsville to Socorro (Texas) | 1,943.18 mi (3,127.24 km) |
| Holtsville to Soddy-Daisy (Tennessee) | 762.52 mi (1,227.16 km) |
| Holtsville to Solana Beach (California) | 2,474.62 mi (3,982.52 km) |
| Holtsville to Soledad (California) | 2,591.43 mi (4,170.51 km) |
| Holtsville to Solon (Ohio) | 438.74 mi (706.08 km) |
| Holtsville to Somers Point (New Jersey) | 132.29 mi (212.89 km) |
| Holtsville to Somerset (Kentucky) | 672.11 mi (1,081.66 km) |
| Holtsville to Somerset (New Jersey) | 79.17 mi (127.41 km) |
