| Holtsville to Silver Firs (Washington) | 2,432.46 mi (3,914.66 km) |
| Holtsville to Silver Spring (Maryland) | 244.99 mi (394.27 km) |
| Holtsville to Silver Springs Shores (Florida) | 953.45 mi (1,534.44 km) |
| Holtsville to Silverdale (Washington) | 2,458.76 mi (3,957.00 km) |
| Holtsville to Silverton (Oregon) | 2,493.87 mi (4,013.49 km) |
| Holtsville to Simi Valley (California) | 2,515.56 mi (4,048.40 km) |
| Holtsville to Simpsonville (South Carolina) | 654.95 mi (1,054.04 km) |
| Holtsville to Sioux City (Iowa) | 1,206.95 mi (1,942.40 km) |
| Holtsville to Sioux Falls (South Dakota) | 1,223.12 mi (1,968.42 km) |
| Holtsville to Skokie (Illinois) | 765.06 mi (1,231.24 km) |
| Holtsville to Sleepy Hollow (New York) | 47.35 mi (76.20 km) |
| Holtsville to Slidell (Louisiana) | 1,185.57 mi (1,907.99 km) |
| Holtsville to Smithfield (North Carolina) | 465.74 mi (749.53 km) |
| Holtsville to Smithfield (Utah) | 1,996.34 mi (3,212.81 km) |
| Holtsville to Smithville (Missouri) | 1,139.19 mi (1,833.35 km) |
