| Holtsville to Seymour (Tennessee) | 672.93 mi (1,082.97 km) |
| Holtsville to Shady Hills (Florida) | 1,011.93 mi (1,628.54 km) |
| Holtsville to Shafter (California) | 2,505.81 mi (4,032.71 km) |
| Holtsville to Shaker Heights (Ohio) | 444.70 mi (715.67 km) |
| Holtsville to Shakopee (Minnesota) | 1,068.33 mi (1,719.32 km) |
| Holtsville to Sharon (Pennsylvania) | 389.58 mi (626.97 km) |
| Holtsville to Sharonville (Ohio) | 609.75 mi (981.29 km) |
| Holtsville to Shasta Lake (California) | 2,547.06 mi (4,099.10 km) |
| Holtsville to Shawnee (Kansas) | 1,156.98 mi (1,861.98 km) |
| Holtsville to Shawnee (Oklahoma) | 1,349.63 mi (2,172.02 km) |
| Holtsville to Sheboygan (Wisconsin) | 776.43 mi (1,249.55 km) |
| Holtsville to Shelby (North Carolina) | 599.04 mi (964.06 km) |
| Holtsville to Shelbyville (Indiana) | 677.46 mi (1,090.26 km) |
| Holtsville to Shelbyville (Kentucky) | 673.36 mi (1,083.67 km) |
| Holtsville to Shelbyville (Tennessee) | 814.47 mi (1,310.76 km) |
