| Holtsville to Security-Widefield (Colorado) | 1,678.47 mi (2,701.23 km) |
| Holtsville to Sedalia (Missouri) | 1,079.73 mi (1,737.66 km) |
| Holtsville to Sedro-Woolley (Washington) | 2,431.05 mi (3,912.39 km) |
| Holtsville to Seguin (Texas) | 1,598.43 mi (2,572.42 km) |
| Holtsville to Selden (New York) | 4.08 mi (6.56 km) |
| Holtsville to Selma (Alabama) | 966.67 mi (1,555.71 km) |
| Holtsville to Selma (California) | 2,498.93 mi (4,021.64 km) |
| Holtsville to Selma (Texas) | 1,615.41 mi (2,599.75 km) |
| Holtsville to Seminole (Florida) | 1,052.78 mi (1,694.28 km) |
| Holtsville to Seven Hills (Ohio) | 450.82 mi (725.52 km) |
| Holtsville to Seven Oaks (South Carolina) | 644.34 mi (1,036.96 km) |
| Holtsville to Severn (Maryland) | 225.34 mi (362.65 km) |
| Holtsville to Severna Park (Maryland) | 221.45 mi (356.39 km) |
| Holtsville to Sevierville (Tennessee) | 663.33 mi (1,067.52 km) |
| Holtsville to Seymour (Indiana) | 692.54 mi (1,114.54 km) |
