| Holtsville to Santa Rosa (California) | 2,612.24 mi (4,203.99 km) |
| Holtsville to Santaquin (Utah) | 2,023.20 mi (3,256.02 km) |
| Holtsville to Santee (California) | 2,464.55 mi (3,966.30 km) |
| Holtsville to Sapulpa (Oklahoma) | 1,287.40 mi (2,071.87 km) |
| Holtsville to Saraland (Alabama) | 1,085.95 mi (1,747.67 km) |
| Holtsville to Sarasota (Florida) | 1,076.43 mi (1,732.34 km) |
| Holtsville to Sarasota Springs (Florida) | 1,076.31 mi (1,732.16 km) |
| Holtsville to Saratoga (California) | 2,605.78 mi (4,193.60 km) |
| Holtsville to Saratoga Springs (New York) | 160.29 mi (257.96 km) |
| Holtsville to Saratoga Springs (Utah) | 2,023.11 mi (3,255.88 km) |
| Holtsville to Sartell (Minnesota) | 1,112.98 mi (1,791.17 km) |
| Holtsville to Satellite Beach (Florida) | 972.27 mi (1,564.72 km) |
| Holtsville to Sauk Rapids (Minnesota) | 1,109.56 mi (1,785.66 km) |
| Holtsville to Sault Ste. Marie (Michigan) | 687.53 mi (1,106.48 km) |
| Holtsville to Savage (Minnesota) | 1,062.61 mi (1,710.10 km) |
