| Holtsville to Saddlebrooke (Arizona) | 2,154.09 mi (3,466.67 km) |
| Holtsville to Safety Harbor (Florida) | 1,040.25 mi (1,674.11 km) |
| Holtsville to Saginaw (Michigan) | 586.73 mi (944.25 km) |
| Holtsville to Saginaw (Texas) | 1,446.54 mi (2,327.97 km) |
| Holtsville to Sahuarita (Arizona) | 2,178.30 mi (3,505.63 km) |
| Holtsville to Saks (Alabama) | 856.92 mi (1,379.08 km) |
| Holtsville to Salem (Massachusetts) | 161.35 mi (259.66 km) |
| Holtsville to Salem (Ohio) | 407.76 mi (656.22 km) |
| Holtsville to Salem (Oregon) | 2,506.64 mi (4,034.04 km) |
| Holtsville to Salem (Virginia) | 447.96 mi (720.92 km) |
| Holtsville to Salem Lakes (Wisconsin) | 786.53 mi (1,265.80 km) |
| Holtsville to Salida (California) | 2,546.74 mi (4,098.58 km) |
| Holtsville to Salina (Kansas) | 1,306.96 mi (2,103.35 km) |
| Holtsville to Salinas (California) | 2,600.06 mi (4,184.40 km) |
| Holtsville to Salisbury (Maryland) | 215.99 mi (347.60 km) |
