| Holtsville to Oswego (Illinois) | 795.65 mi (1,280.48 km) |
| Holtsville to Oswego (New York) | 254.13 mi (408.99 km) |
| Holtsville to Otsego (Minnesota) | 1,080.23 mi (1,738.47 km) |
| Holtsville to Ottawa (Illinois) | 821.60 mi (1,322.24 km) |
| Holtsville to Ottawa (Kansas) | 1,187.67 mi (1,911.37 km) |
| Holtsville to Ottumwa (Iowa) | 1,009.57 mi (1,624.74 km) |
| Holtsville to Overland (Missouri) | 930.19 mi (1,497.00 km) |
| Holtsville to Overland Park (Kansas) | 1,152.72 mi (1,855.13 km) |
| Holtsville to Overlea (Maryland) | 209.05 mi (336.43 km) |
| Holtsville to Oviedo (Florida) | 957.56 mi (1,541.04 km) |
| Holtsville to Owasso (Oklahoma) | 1,266.35 mi (2,038.00 km) |
| Holtsville to Owatonna (Minnesota) | 1,050.89 mi (1,691.24 km) |
| Holtsville to Owensboro (Kentucky) | 780.63 mi (1,256.30 km) |
| Holtsville to Owings Mills (Maryland) | 220.34 mi (354.61 km) |
| Holtsville to Owosso (Michigan) | 591.45 mi (951.85 km) |
