| Holtsville to Orangevale (California) | 2,530.97 mi (4,073.20 km) |
| Holtsville to Orchards (Washington) | 2,473.01 mi (3,979.93 km) |
| Holtsville to Orcutt (California) | 2,585.78 mi (4,161.42 km) |
| Holtsville to Oregon (Ohio) | 542.52 mi (873.10 km) |
| Holtsville to Oregon (Wisconsin) | 852.12 mi (1,371.35 km) |
| Holtsville to Oregon City (Oregon) | 2,480.36 mi (3,991.75 km) |
| Holtsville to Orem (Utah) | 2,012.83 mi (3,239.34 km) |
| Holtsville to Orinda (California) | 2,598.68 mi (4,182.17 km) |
| Holtsville to Orland Park (Illinois) | 771.19 mi (1,241.10 km) |
| Holtsville to Orlando (Florida) | 972.79 mi (1,565.56 km) |
| Holtsville to Ormond Beach (Florida) | 915.79 mi (1,473.82 km) |
| Holtsville to Oro Valley (Arizona) | 2,163.65 mi (3,482.06 km) |
| Holtsville to Oroville (California) | 2,530.51 mi (4,072.46 km) |
| Holtsville to Oshkosh (Wisconsin) | 820.58 mi (1,320.60 km) |
| Holtsville to Oskaloosa (Iowa) | 1,019.38 mi (1,640.54 km) |
