| Holtsville to Des Plaines (Illinois) | 773.31 mi (1,244.52 km) |
| Holtsville to Desert Hot Springs (California) | 2,409.28 mi (3,877.36 km) |
| Holtsville to DeSoto (Texas) | 1,430.32 mi (2,301.87 km) |
| Holtsville to Destin (Florida) | 1,040.20 mi (1,674.04 km) |
| Holtsville to Destrehan (Louisiana) | 1,226.58 mi (1,973.99 km) |
| Holtsville to Detroit (Michigan) | 530.55 mi (853.84 km) |
| Holtsville to Diamond Bar (California) | 2,474.48 mi (3,982.30 km) |
| Holtsville to Diamond Springs (California) | 2,511.41 mi (4,041.72 km) |
| Holtsville to Dickinson (North Dakota) | 1,530.25 mi (2,462.70 km) |
| Holtsville to Dickinson (Texas) | 1,464.29 mi (2,356.55 km) |
| Holtsville to Dickson (Tennessee) | 840.36 mi (1,352.43 km) |
| Holtsville to Difficult Run (Virginia) | 263.59 mi (424.20 km) |
| Holtsville to Dinuba (California) | 2,488.44 mi (4,004.76 km) |
| Holtsville to Discovery Bay (California) | 2,568.39 mi (4,133.43 km) |
| Holtsville to Dix Hills (New York) | 15.33 mi (24.66 km) |
