| Hilton Head Island to Worthington (Ohio) | 560.66 mi (902.29 km) |
| Hilton Head Island to Wright (Florida) | 368.03 mi (592.28 km) |
| Hilton Head Island to Wyandanch (New York) | 719.26 mi (1,157.54 km) |
| Hilton Head Island to Wyandotte (Michigan) | 704.89 mi (1,134.41 km) |
| Hilton Head Island to Wylie (Texas) | 918.58 mi (1,478.32 km) |
| Hilton Head Island to Wyndham (Virginia) | 419.61 mi (675.30 km) |
| Hilton Head Island to Wyoming (Michigan) | 787.28 mi (1,267.01 km) |
| Hilton Head Island to Wyomissing (Pennsylvania) | 622.14 mi (1,001.24 km) |
| Hilton Head Island to Xenia (Ohio) | 547.55 mi (881.19 km) |
| Hilton Head Island to Yakima (Washington) | 2,315.12 mi (3,725.83 km) |
| Hilton Head Island to Yankton (South Dakota) | 1,170.08 mi (1,883.06 km) |
| Hilton Head Island to Yauco (Puerto Rico) | 1,305.55 mi (2,101.08 km) |
| Hilton Head Island to Yazoo City (Mississippi) | 564.33 mi (908.20 km) |
| Hilton Head Island to Yeadon (Pennsylvania) | 616.51 mi (992.18 km) |
| Hilton Head Island to Yelm (Washington) | 2,416.12 mi (3,888.37 km) |
