| Hilton Head Island to Somersworth (New Hampshire) | 933.92 mi (1,502.99 km) |
| Hilton Head Island to Somerton (Arizona) | 1,972.31 mi (3,174.12 km) |
| Hilton Head Island to Somerville (Massachusetts) | 880.79 mi (1,417.50 km) |
| Hilton Head Island to Somerville (New Jersey) | 671.82 mi (1,081.19 km) |
| Hilton Head Island to Sonoma (California) | 2,370.82 mi (3,815.46 km) |
| Hilton Head Island to Soquel (California) | 2,348.37 mi (3,779.33 km) |
| Hilton Head Island to South Bend (Indiana) | 722.50 mi (1,162.75 km) |
| Hilton Head Island to South Bradenton (Florida) | 344.65 mi (554.66 km) |
| Hilton Head Island to South Burlington (Vermont) | 940.04 mi (1,512.85 km) |
| Hilton Head Island to South Charleston (West Virginia) | 428.60 mi (689.76 km) |
| Hilton Head Island to South Daytona (Florida) | 209.48 mi (337.13 km) |
| Hilton Head Island to South El Monte (California) | 2,150.31 mi (3,460.58 km) |
| Hilton Head Island to South Elgin (Illinois) | 794.43 mi (1,278.50 km) |
| Hilton Head Island to South Euclid (Ohio) | 646.36 mi (1,040.21 km) |
| Hilton Head Island to South Farmingdale (New York) | 714.85 mi (1,150.43 km) |
