| Hilton Head Island to Shoreview (Minnesota) | 1,111.04 mi (1,788.04 km) |
| Hilton Head Island to Shorewood (Illinois) | 764.55 mi (1,230.43 km) |
| Hilton Head Island to Shorewood (Wisconsin) | 847.62 mi (1,364.11 km) |
| Hilton Head Island to Short Hills (New Jersey) | 689.64 mi (1,109.86 km) |
| Hilton Head Island to Short Pump (Virginia) | 417.10 mi (671.25 km) |
| Hilton Head Island to Show Low (Arizona) | 1,693.01 mi (2,724.64 km) |
| Hilton Head Island to Shreveport (Louisiana) | 761.42 mi (1,225.39 km) |
| Hilton Head Island to Sicklerville (New Jersey) | 612.97 mi (986.48 km) |
| Hilton Head Island to Sidney (Ohio) | 590.99 mi (951.11 km) |
| Hilton Head Island to Sierra Madre (California) | 2,149.41 mi (3,459.13 km) |
| Hilton Head Island to Sierra Vista (Arizona) | 1,729.76 mi (2,783.78 km) |
| Hilton Head Island to Sierra Vista Southeast (Arizona) | 1,725.24 mi (2,776.50 km) |
| Hilton Head Island to Signal Hill (California) | 2,159.30 mi (3,475.06 km) |
| Hilton Head Island to Sikeston (Missouri) | 598.15 mi (962.63 km) |
| Hilton Head Island to Siloam Springs (Arkansas) | 833.71 mi (1,341.73 km) |
