| Hilton Head Island to Oakley (California) | 2,330.29 mi (3,750.23 km) |
| Hilton Head Island to Oakton (Virginia) | 501.71 mi (807.43 km) |
| Hilton Head Island to Oakville (Missouri) | 690.73 mi (1,111.62 km) |
| Hilton Head Island to Oatfield (Oregon) | 2,398.74 mi (3,860.39 km) |
| Hilton Head Island to Ocala (Florida) | 224.11 mi (360.67 km) |
| Hilton Head Island to Ocean Acres (New Jersey) | 634.60 mi (1,021.29 km) |
| Hilton Head Island to Ocean City (New Jersey) | 598.06 mi (962.49 km) |
| Hilton Head Island to Ocean Pines (Maryland) | 531.76 mi (855.78 km) |
| Hilton Head Island to Ocean Pointe (Hawaii) | 4,729.72 mi (7,611.74 km) |
| Hilton Head Island to Ocean Springs (Mississippi) | 490.01 mi (788.59 km) |
| Hilton Head Island to Oceanside (California) | 2,115.76 mi (3,404.98 km) |
| Hilton Head Island to Oceanside (New York) | 704.24 mi (1,133.37 km) |
| Hilton Head Island to Ocoee (Florida) | 253.76 mi (408.38 km) |
| Hilton Head Island to Oconomowoc (Wisconsin) | 863.80 mi (1,390.15 km) |
| Hilton Head Island to Odenton (Maryland) | 526.75 mi (847.72 km) |
