| Hilton Head Island to Merrick (New York) | 707.86 mi (1,139.20 km) |
| Hilton Head Island to Merrifield (Virginia) | 502.02 mi (807.92 km) |
| Hilton Head Island to Merrillville (Indiana) | 736.60 mi (1,185.44 km) |
| Hilton Head Island to Merritt Island (Florida) | 267.83 mi (431.03 km) |
| Hilton Head Island to Mesa (Arizona) | 1,793.96 mi (2,887.10 km) |
| Hilton Head Island to Mesquite (Nevada) | 1,917.58 mi (3,086.05 km) |
| Hilton Head Island to Mesquite (Texas) | 923.08 mi (1,485.56 km) |
| Hilton Head Island to Metairie (Louisiana) | 577.79 mi (929.86 km) |
| Hilton Head Island to Methuen Town (Massachusetts) | 896.30 mi (1,442.45 km) |
| Hilton Head Island to Metuchen (New Jersey) | 677.29 mi (1,089.99 km) |
| Hilton Head Island to Mexico (Missouri) | 787.46 mi (1,267.29 km) |
| Hilton Head Island to Miami (Florida) | 443.78 mi (714.20 km) |
| Hilton Head Island to Miami (Oklahoma) | 865.67 mi (1,393.17 km) |
| Hilton Head Island to Miami Beach (Florida) | 441.84 mi (711.07 km) |
| Hilton Head Island to Miami Gardens (Florida) | 432.66 mi (696.30 km) |
