| Hilton Head Island to McKeesport (Pennsylvania) | 565.51 mi (910.10 km) |
| Hilton Head Island to McKinleyville (California) | 2,453.22 mi (3,948.08 km) |
| Hilton Head Island to McKinney (Texas) | 927.25 mi (1,492.26 km) |
| Hilton Head Island to McLean (Virginia) | 507.52 mi (816.78 km) |
| Hilton Head Island to McMinnville (Oregon) | 2,425.82 mi (3,903.98 km) |
| Hilton Head Island to McMinnville (Tennessee) | 376.13 mi (605.32 km) |
| Hilton Head Island to McNair (Virginia) | 503.35 mi (810.06 km) |
| Hilton Head Island to McPherson (Kansas) | 1,042.96 mi (1,678.48 km) |
| Hilton Head Island to Mead Valley (California) | 2,108.77 mi (3,393.74 km) |
| Hilton Head Island to Meadow Woods (Florida) | 266.31 mi (428.59 km) |
| Hilton Head Island to Meadowbrook (Virginia) | 406.91 mi (654.86 km) |
| Hilton Head Island to Meadville (Pennsylvania) | 654.33 mi (1,053.04 km) |
| Hilton Head Island to Mebane (North Carolina) | 282.08 mi (453.96 km) |
| Hilton Head Island to Mechanicsville (Virginia) | 421.91 mi (679.01 km) |
| Hilton Head Island to Medford (Massachusetts) | 882.28 mi (1,419.90 km) |
