| Hilton Head Island to Eugene (Oregon) | 2,413.85 mi (3,884.71 km) |
| Hilton Head Island to Euless (Texas) | 951.54 mi (1,531.35 km) |
| Hilton Head Island to Eureka (California) | 2,456.92 mi (3,954.03 km) |
| Hilton Head Island to Eureka (Missouri) | 707.34 mi (1,138.35 km) |
| Hilton Head Island to Eustis (Florida) | 236.82 mi (381.13 km) |
| Hilton Head Island to Evans (Colorado) | 1,444.78 mi (2,325.16 km) |
| Hilton Head Island to Evans (Georgia) | 124.30 mi (200.04 km) |
| Hilton Head Island to Evanston (Illinois) | 780.48 mi (1,256.06 km) |
| Hilton Head Island to Evanston (Wyoming) | 1,775.78 mi (2,857.85 km) |
| Hilton Head Island to Evansville (Indiana) | 554.31 mi (892.07 km) |
| Hilton Head Island to Everett (Massachusetts) | 883.16 mi (1,421.31 km) |
| Hilton Head Island to Everett (Washington) | 2,407.94 mi (3,875.20 km) |
| Hilton Head Island to Evergreen Park (Illinois) | 761.61 mi (1,225.69 km) |
| Hilton Head Island to Ewa Beach (Hawaii) | 4,728.37 mi (7,609.57 km) |
| Hilton Head Island to Ewa Gentry (Hawaii) | 4,728.93 mi (7,610.48 km) |
