| Hilton Head Island to Eatontown (New Jersey) | 672.19 mi (1,081.79 km) |
| Hilton Head Island to Eau Claire (Wisconsin) | 1,046.28 mi (1,683.82 km) |
| Hilton Head Island to Echelon (New Jersey) | 618.86 mi (995.96 km) |
| Hilton Head Island to Eden (North Carolina) | 303.50 mi (488.44 km) |
| Hilton Head Island to Eden Prairie (Minnesota) | 1,109.39 mi (1,785.40 km) |
| Hilton Head Island to Edgewater (Florida) | 223.47 mi (359.65 km) |
| Hilton Head Island to Edgewater (New Jersey) | 704.79 mi (1,134.24 km) |
| Hilton Head Island to Edgewood (Maryland) | 558.17 mi (898.30 km) |
| Hilton Head Island to Edgewood (Washington) | 2,403.75 mi (3,868.46 km) |
| Hilton Head Island to Edina (Minnesota) | 1,108.31 mi (1,783.66 km) |
| Hilton Head Island to Edinburg (Texas) | 1,123.38 mi (1,807.91 km) |
| Hilton Head Island to Edmond (Oklahoma) | 983.86 mi (1,583.37 km) |
| Hilton Head Island to Edmonds (Washington) | 2,414.48 mi (3,885.73 km) |
| Hilton Head Island to Edwards (Colorado) | 1,529.58 mi (2,461.62 km) |
| Hilton Head Island to Edwardsville (Illinois) | 690.81 mi (1,111.75 km) |
