| Hilton Head Island to Eagan (Minnesota) | 1,098.07 mi (1,767.17 km) |
| Hilton Head Island to Eagle (Idaho) | 2,078.75 mi (3,345.43 km) |
| Hilton Head Island to Eagle Mountain (Utah) | 1,819.08 mi (2,927.53 km) |
| Hilton Head Island to Eagle Pass (Texas) | 1,197.88 mi (1,927.81 km) |
| Hilton Head Island to Easley (South Carolina) | 210.11 mi (338.14 km) |
| Hilton Head Island to East Bakersfield (California) | 2,192.52 mi (3,528.51 km) |
| Hilton Head Island to East Bethel (Minnesota) | 1,127.41 mi (1,814.40 km) |
| Hilton Head Island to East Chicago (Indiana) | 750.50 mi (1,207.81 km) |
| Hilton Head Island to East Cleveland (Ohio) | 647.09 mi (1,041.40 km) |
| Hilton Head Island to East Glenville (New York) | 826.24 mi (1,329.71 km) |
| Hilton Head Island to East Grand Rapids (Michigan) | 789.05 mi (1,269.85 km) |
| Hilton Head Island to East Hemet (California) | 2,090.06 mi (3,363.63 km) |
| Hilton Head Island to East Highland Park (Virginia) | 418.13 mi (672.91 km) |
| Hilton Head Island to East Honolulu (Hawaii) | 4,712.67 mi (7,584.31 km) |
| Hilton Head Island to East Islip (New York) | 723.56 mi (1,164.45 km) |
