| Hilton Head Island to Delaware (Ohio) | 574.08 mi (923.90 km) |
| Hilton Head Island to Delhi (California) | 2,282.06 mi (3,672.62 km) |
| Hilton Head Island to Delray Beach (Florida) | 398.21 mi (640.85 km) |
| Hilton Head Island to Deltona (Florida) | 228.61 mi (367.92 km) |
| Hilton Head Island to Deming (New Mexico) | 1,574.07 mi (2,533.23 km) |
| Hilton Head Island to Denison (Texas) | 923.09 mi (1,485.58 km) |
| Hilton Head Island to Dent (Ohio) | 531.07 mi (854.68 km) |
| Hilton Head Island to Denton (Texas) | 954.70 mi (1,536.43 km) |
| Hilton Head Island to Dentsville (South Carolina) | 130.83 mi (210.56 km) |
| Hilton Head Island to Denver (Colorado) | 1,441.29 mi (2,319.53 km) |
| Hilton Head Island to Depew (New York) | 749.19 mi (1,205.71 km) |
| Hilton Head Island to Derby (Connecticut) | 759.95 mi (1,223.02 km) |
| Hilton Head Island to Derby (Kansas) | 1,004.65 mi (1,616.83 km) |
| Hilton Head Island to Des Moines (Iowa) | 960.03 mi (1,545.02 km) |
| Hilton Head Island to Des Moines (Washington) | 2,407.27 mi (3,874.12 km) |
