| Hilton Head Island to Clarksdale (Mississippi) | 584.13 mi (940.07 km) |
| Hilton Head Island to Clarkston (Georgia) | 231.21 mi (372.10 km) |
| Hilton Head Island to Clarksville (Indiana) | 509.37 mi (819.75 km) |
| Hilton Head Island to Clarksville (Tennessee) | 482.32 mi (776.21 km) |
| Hilton Head Island to Clawson (Michigan) | 726.88 mi (1,169.80 km) |
| Hilton Head Island to Clay (Alabama) | 355.24 mi (571.70 km) |
| Hilton Head Island to Clayton (California) | 2,343.24 mi (3,771.09 km) |
| Hilton Head Island to Clayton (Missouri) | 699.22 mi (1,125.28 km) |
| Hilton Head Island to Clayton (North Carolina) | 273.57 mi (440.26 km) |
| Hilton Head Island to Clayton (Ohio) | 566.89 mi (912.32 km) |
| Hilton Head Island to Clearfield (Utah) | 1,828.06 mi (2,941.98 km) |
| Hilton Head Island to Clearlake (California) | 2,378.33 mi (3,827.55 km) |
| Hilton Head Island to Clearwater (Florida) | 314.80 mi (506.62 km) |
| Hilton Head Island to Cleburne (Texas) | 972.65 mi (1,565.33 km) |
| Hilton Head Island to Clemmons (North Carolina) | 266.29 mi (428.55 km) |
