| Hilton Head Island to Altus (Oklahoma) | 1,081.97 mi (1,741.27 km) |
| Hilton Head Island to Alum Rock (California) | 2,339.73 mi (3,765.43 km) |
| Hilton Head Island to Alvin (Texas) | 883.94 mi (1,422.56 km) |
| Hilton Head Island to Amarillo (Texas) | 1,227.20 mi (1,974.99 km) |
| Hilton Head Island to Amelia (Ohio) | 510.97 mi (822.33 km) |
| Hilton Head Island to American Canyon (California) | 2,360.26 mi (3,798.47 km) |
| Hilton Head Island to American Fork (Utah) | 1,808.45 mi (2,910.42 km) |
| Hilton Head Island to Americus (Georgia) | 203.47 mi (327.45 km) |
| Hilton Head Island to Ames (Iowa) | 980.19 mi (1,577.47 km) |
| Hilton Head Island to Amherst (Ohio) | 641.75 mi (1,032.79 km) |
| Hilton Head Island to Ammon (Idaho) | 1,858.57 mi (2,991.08 km) |
| Hilton Head Island to Amsterdam (New York) | 824.54 mi (1,326.97 km) |
| Hilton Head Island to Anacortes (Washington) | 2,436.28 mi (3,920.82 km) |
| Hilton Head Island to Anaheim (California) | 2,141.29 mi (3,446.08 km) |
| Hilton Head Island to Anchorage (Alaska) | 3,585.13 mi (5,769.70 km) |
