| Hilton Head Island to Scarborough | 4,075.13 mi (6,558.29 km) |
| Hilton Head Island to Scartho | 4,099.29 mi (6,597.16 km) |
| Hilton Head Island to Scunthorpe | 4,076.38 mi (6,560.30 km) |
| Hilton Head Island to Seacombe | 3,983.57 mi (6,410.94 km) |
| Hilton Head Island to Seacroft | 4,040.35 mi (6,502.31 km) |
| Hilton Head Island to Seaford | 4,155.80 mi (6,688.12 km) |
| Hilton Head Island to Seaham | 4,029.91 mi (6,485.51 km) |
| Hilton Head Island to Sedgley | 4,033.29 mi (6,490.95 km) |
| Hilton Head Island to Selby | 4,056.47 mi (6,528.26 km) |
| Hilton Head Island to Selsey | 4,118.92 mi (6,628.75 km) |
| Hilton Head Island to Selston | 4,058.44 mi (6,531.43 km) |
| Hilton Head Island to Sevenoaks | 4,150.11 mi (6,678.96 km) |
| Hilton Head Island to Shanklin | 4,104.42 mi (6,605.43 km) |
| Hilton Head Island to Sheerness | 4,170.91 mi (6,712.43 km) |
| Hilton Head Island to Sheffield | 4,046.71 mi (6,512.55 km) |
