| Highlands Ranch to St. George (Utah) | 496.39 mi (798.86 km) |
| Highlands Ranch to St. Helens (Oregon) | 1,002.75 mi (1,613.77 km) |
| Highlands Ranch to St. James (New York) | 1,672.23 mi (2,691.20 km) |
| Highlands Ranch to St. John (Indiana) | 927.29 mi (1,492.33 km) |
| Highlands Ranch to St. Joseph (Missouri) | 539.87 mi (868.84 km) |
| Highlands Ranch to St. Louis (Missouri) | 791.30 mi (1,273.47 km) |
| Highlands Ranch to St. Louis Park (Minnesota) | 700.35 mi (1,127.10 km) |
| Highlands Ranch to St. Marys (Georgia) | 1,448.85 mi (2,331.71 km) |
| Highlands Ranch to St. Marys (Pennsylvania) | 1,389.81 mi (2,236.69 km) |
| Highlands Ranch to St. Matthews (Kentucky) | 1,041.40 mi (1,675.98 km) |
| Highlands Ranch to St. Michael (Minnesota) | 694.94 mi (1,118.40 km) |
| Highlands Ranch to St. Paul (Minnesota) | 711.60 mi (1,145.21 km) |
| Highlands Ranch to St. Peter (Minnesota) | 654.44 mi (1,053.22 km) |
| Highlands Ranch to St. Peters (Missouri) | 770.51 mi (1,240.02 km) |
| Highlands Ranch to St. Petersburg (Florida) | 1,511.37 mi (2,432.32 km) |
