| Highlands Ranch to Security-Widefield (Colorado) | 56.49 mi (90.91 km) |
| Highlands Ranch to Sedalia (Missouri) | 631.30 mi (1,015.98 km) |
| Highlands Ranch to Sedro-Woolley (Washington) | 1,054.04 mi (1,696.31 km) |
| Highlands Ranch to Seguin (Texas) | 794.12 mi (1,278.02 km) |
| Highlands Ranch to Selden (New York) | 1,677.74 mi (2,700.06 km) |
| Highlands Ranch to Selma (Alabama) | 1,114.45 mi (1,793.53 km) |
| Highlands Ranch to Selma (California) | 821.63 mi (1,322.29 km) |
| Highlands Ranch to Selma (Texas) | 784.66 mi (1,262.79 km) |
| Highlands Ranch to Seminole (Florida) | 1,503.52 mi (2,419.68 km) |
| Highlands Ranch to Seven Hills (Ohio) | 1,227.56 mi (1,975.56 km) |
| Highlands Ranch to Seven Oaks (South Carolina) | 1,367.30 mi (2,200.45 km) |
| Highlands Ranch to Severn (Maryland) | 1,504.97 mi (2,422.01 km) |
| Highlands Ranch to Severna Park (Maryland) | 1,512.26 mi (2,433.74 km) |
| Highlands Ranch to Sevierville (Tennessee) | 1,193.73 mi (1,921.12 km) |
| Highlands Ranch to Seymour (Indiana) | 1,019.86 mi (1,641.30 km) |
