| Highlands Ranch to Santa Rosa (California) | 953.88 mi (1,535.12 km) |
| Highlands Ranch to Santaquin (Utah) | 363.55 mi (585.08 km) |
| Highlands Ranch to Santee (California) | 812.57 mi (1,307.70 km) |
| Highlands Ranch to Sapulpa (Oklahoma) | 542.11 mi (872.44 km) |
| Highlands Ranch to Saraland (Alabama) | 1,123.23 mi (1,807.67 km) |
| Highlands Ranch to Sarasota (Florida) | 1,536.81 mi (2,473.25 km) |
| Highlands Ranch to Sarasota Springs (Florida) | 1,541.38 mi (2,480.62 km) |
| Highlands Ranch to Saratoga (California) | 935.24 mi (1,505.13 km) |
| Highlands Ranch to Saratoga Springs (New York) | 1,627.68 mi (2,619.50 km) |
| Highlands Ranch to Saratoga Springs (Utah) | 371.93 mi (598.57 km) |
| Highlands Ranch to Sartell (Minnesota) | 688.49 mi (1,108.02 km) |
| Highlands Ranch to Satellite Beach (Florida) | 1,595.92 mi (2,568.39 km) |
| Highlands Ranch to Sauk Rapids (Minnesota) | 690.39 mi (1,111.07 km) |
| Highlands Ranch to Sault Ste. Marie (Michigan) | 1,141.35 mi (1,836.83 km) |
| Highlands Ranch to Savage (Minnesota) | 694.19 mi (1,117.18 km) |
