| Highlands Ranch to Sanford (Maine) | 1,778.39 mi (2,862.04 km) |
| Highlands Ranch to Sanford (North Carolina) | 1,435.91 mi (2,310.87 km) |
| Highlands Ranch to Sanger (California) | 815.83 mi (1,312.96 km) |
| Highlands Ranch to Santa Ana (California) | 819.34 mi (1,318.60 km) |
| Highlands Ranch to Santa Barbara (California) | 885.98 mi (1,425.84 km) |
| Highlands Ranch to Santa Clara (California) | 930.46 mi (1,497.42 km) |
| Highlands Ranch to Santa Clara (Oregon) | 984.63 mi (1,584.61 km) |
| Highlands Ranch to Santa Clarita (California) | 825.07 mi (1,327.83 km) |
| Highlands Ranch to Santa Cruz (California) | 941.02 mi (1,514.43 km) |
| Highlands Ranch to Santa Fe (New Mexico) | 273.73 mi (440.53 km) |
| Highlands Ranch to Santa Fe (Texas) | 897.78 mi (1,444.84 km) |
| Highlands Ranch to Santa Fe Springs (California) | 820.80 mi (1,320.95 km) |
| Highlands Ranch to Santa Maria (California) | 907.23 mi (1,460.04 km) |
| Highlands Ranch to Santa Monica (California) | 837.99 mi (1,348.62 km) |
| Highlands Ranch to Santa Paula (California) | 855.55 mi (1,376.87 km) |
