| Highlands Ranch to San Diego (California) | 819.87 mi (1,319.45 km) |
| Highlands Ranch to San Diego Country Estates (California) | 796.98 mi (1,282.62 km) |
| Highlands Ranch to San Dimas (California) | 802.08 mi (1,290.83 km) |
| Highlands Ranch to San Fernando (California) | 826.50 mi (1,330.12 km) |
| Highlands Ranch to San Francisco (California) | 949.43 mi (1,527.96 km) |
| Highlands Ranch to San Gabriel (California) | 816.72 mi (1,314.38 km) |
| Highlands Ranch to San Germán (Puerto Rico) | 2,702.67 mi (4,349.53 km) |
| Highlands Ranch to San Jacinto (California) | 774.46 mi (1,246.37 km) |
| Highlands Ranch to San Jose (California) | 925.19 mi (1,488.95 km) |
| Highlands Ranch to San Juan (Puerto Rico) | 2,737.21 mi (4,405.12 km) |
| Highlands Ranch to San Juan (Texas) | 1,002.98 mi (1,614.13 km) |
| Highlands Ranch to San Juan Capistrano (California) | 817.48 mi (1,315.61 km) |
| Highlands Ranch to San Leandro (California) | 935.01 mi (1,504.75 km) |
| Highlands Ranch to San Lorenzo (California) | 934.12 mi (1,503.33 km) |
| Highlands Ranch to San Luis (Arizona) | 729.58 mi (1,174.15 km) |
