| Highlands Ranch to Orangevale (California) | 871.95 mi (1,403.26 km) |
| Highlands Ranch to Orchards (Washington) | 985.90 mi (1,586.66 km) |
| Highlands Ranch to Orcutt (California) | 908.05 mi (1,461.36 km) |
| Highlands Ranch to Oregon (Ohio) | 1,136.33 mi (1,828.75 km) |
| Highlands Ranch to Oregon (Wisconsin) | 841.28 mi (1,353.90 km) |
| Highlands Ranch to Oregon City (Oregon) | 981.10 mi (1,578.92 km) |
| Highlands Ranch to Orem (Utah) | 360.27 mi (579.80 km) |
| Highlands Ranch to Orinda (California) | 933.38 mi (1,502.13 km) |
| Highlands Ranch to Orland Park (Illinois) | 907.60 mi (1,460.64 km) |
| Highlands Ranch to Orlando (Florida) | 1,547.57 mi (2,490.58 km) |
| Highlands Ranch to Ormond Beach (Florida) | 1,526.83 mi (2,457.20 km) |
| Highlands Ranch to Oro Valley (Arizona) | 595.34 mi (958.11 km) |
| Highlands Ranch to Oroville (California) | 883.10 mi (1,421.21 km) |
| Highlands Ranch to Oshkosh (Wisconsin) | 898.42 mi (1,445.87 km) |
| Highlands Ranch to Oskaloosa (Iowa) | 659.21 mi (1,060.89 km) |
