| Highlands Ranch to Olympia Heights (Florida) | 1,712.91 mi (2,756.66 km) |
| Highlands Ranch to Omaha (Nebraska) | 483.80 mi (778.60 km) |
| Highlands Ranch to On Top of the World Designated Place (Florida) | 1,475.54 mi (2,374.66 km) |
| Highlands Ranch to Onalaska (Wisconsin) | 769.53 mi (1,238.44 km) |
| Highlands Ranch to Oneida (New York) | 1,532.57 mi (2,466.43 km) |
| Highlands Ranch to Oneonta (New York) | 1,564.13 mi (2,517.22 km) |
| Highlands Ranch to Ontario (California) | 794.76 mi (1,279.04 km) |
| Highlands Ranch to Ontario (Oregon) | 690.84 mi (1,111.80 km) |
| Highlands Ranch to Opa-locka (Florida) | 1,709.14 mi (2,750.60 km) |
| Highlands Ranch to Opelika (Alabama) | 1,189.41 mi (1,914.17 km) |
| Highlands Ranch to Opelousas (Louisiana) | 957.29 mi (1,540.60 km) |
| Highlands Ranch to Orange (California) | 813.92 mi (1,309.88 km) |
| Highlands Ranch to Orange (Texas) | 908.35 mi (1,461.84 km) |
| Highlands Ranch to Orange City (Florida) | 1,531.72 mi (2,465.07 km) |
| Highlands Ranch to Orangeburg (South Carolina) | 1,397.24 mi (2,248.64 km) |
