| Highlands Ranch to Elyria (Ohio) | 1,205.16 mi (1,939.51 km) |
| Highlands Ranch to Emeryville (California) | 940.10 mi (1,512.94 km) |
| Highlands Ranch to Emmaus (Pennsylvania) | 1,553.32 mi (2,499.83 km) |
| Highlands Ranch to Emporia (Kansas) | 477.82 mi (768.98 km) |
| Highlands Ranch to Encinitas (California) | 817.14 mi (1,315.06 km) |
| Highlands Ranch to Endicott (New York) | 1,514.46 mi (2,437.28 km) |
| Highlands Ranch to Endwell (New York) | 1,516.53 mi (2,440.62 km) |
| Highlands Ranch to Englewood (Colorado) | 7.35 mi (11.84 km) |
| Highlands Ranch to Englewood (Florida) | 1,561.93 mi (2,513.69 km) |
| Highlands Ranch to Englewood (New Jersey) | 1,629.52 mi (2,622.46 km) |
| Highlands Ranch to Englewood (Ohio) | 1,096.22 mi (1,764.20 km) |
| Highlands Ranch to Enid (Oklahoma) | 443.09 mi (713.09 km) |
| Highlands Ranch to Ennis (Texas) | 682.08 mi (1,097.70 km) |
| Highlands Ranch to Ensley (Florida) | 1,175.90 mi (1,892.43 km) |
| Highlands Ranch to Enterprise (Alabama) | 1,213.51 mi (1,952.95 km) |
