| Hernando to Olympia Heights (Florida) | 853.04 mi (1,372.83 km) |
| Hernando to Omaha (Nebraska) | 551.98 mi (888.32 km) |
| Hernando to On Top of the World Designated Place (Florida) | 600.84 mi (966.96 km) |
| Hernando to Onalaska (Wisconsin) | 627.83 mi (1,010.40 km) |
| Hernando to Oneida (New York) | 954.74 mi (1,536.51 km) |
| Hernando to Oneonta (New York) | 959.42 mi (1,544.04 km) |
| Hernando to Ontario (California) | 1,569.47 mi (2,525.82 km) |
| Hernando to Ontario (Oregon) | 1,564.03 mi (2,517.07 km) |
| Hernando to Opa-locka (Florida) | 847.18 mi (1,363.40 km) |
| Hernando to Opelika (Alabama) | 305.17 mi (491.12 km) |
| Hernando to Opelousas (Louisiana) | 322.55 mi (519.09 km) |
| Hernando to Orange (California) | 1,584.51 mi (2,550.02 km) |
| Hernando to Orange (Texas) | 393.53 mi (633.32 km) |
| Hernando to Orange City (Florida) | 653.54 mi (1,051.77 km) |
| Hernando to Orangeburg (South Carolina) | 529.79 mi (852.62 km) |
