| Hemel Hempstead to Southern Pines (North Carolina) | 3,914.32 mi (6,299.48 km) |
| Hemel Hempstead to Southfield (Michigan) | 3,731.81 mi (6,005.76 km) |
| Hemel Hempstead to Southgate (Michigan) | 3,741.93 mi (6,022.05 km) |
| Hemel Hempstead to Southlake (Texas) | 4,731.74 mi (7,615.00 km) |
| Hemel Hempstead to Spanaway (Washington) | 4,793.37 mi (7,714.18 km) |
| Hemel Hempstead to Spanish Fork (Utah) | 4,866.19 mi (7,831.37 km) |
| Hemel Hempstead to Spanish Lake (Missouri) | 4,172.16 mi (6,714.44 km) |
| Hemel Hempstead to Spanish Springs (Nevada) | 5,141.52 mi (8,274.48 km) |
| Hemel Hempstead to Sparks (Nevada) | 5,147.67 mi (8,284.38 km) |
| Hemel Hempstead to Spartanburg (South Carolina) | 4,029.31 mi (6,484.54 km) |
| Hemel Hempstead to Spearfish (South Dakota) | 4,377.56 mi (7,045.00 km) |
| Hemel Hempstead to Speedway (Indiana) | 3,971.21 mi (6,391.05 km) |
| Hemel Hempstead to Spencer (Iowa) | 4,144.73 mi (6,670.30 km) |
| Hemel Hempstead to Spokane (Washington) | 4,625.82 mi (7,444.53 km) |
| Hemel Hempstead to Spokane Valley (Washington) | 4,620.52 mi (7,436.01 km) |
