| Helena to Enterprise (Nevada) | 750.05 mi (1,207.09 km) |
| Helena to Enumclaw (Washington) | 472.19 mi (759.92 km) |
| Helena to Ephrata (Pennsylvania) | 1,836.22 mi (2,955.11 km) |
| Helena to Erie (Colorado) | 572.50 mi (921.35 km) |
| Helena to Erie (Pennsylvania) | 1,596.83 mi (2,569.84 km) |
| Helena to Erlanger (Kentucky) | 1,476.96 mi (2,376.94 km) |
| Helena to Escanaba (Michigan) | 1,189.29 mi (1,913.98 km) |
| Helena to Escondido (California) | 967.39 mi (1,556.87 km) |
| Helena to Española (New Mexico) | 793.78 mi (1,277.47 km) |
| Helena to Essex (Maryland) | 1,851.02 mi (2,978.93 km) |
| Helena to Essex Junction (Vermont) | 1,869.14 mi (3,008.09 km) |
| Helena to Estelle (Louisiana) | 1,649.10 mi (2,653.97 km) |
| Helena to Estero (Florida) | 2,158.27 mi (3,473.40 km) |
| Helena to Euclid (Ohio) | 1,542.26 mi (2,482.02 km) |
| Helena to Eufaula (Alabama) | 1,745.54 mi (2,809.18 km) |
