| Harrisonburg to Southern Pines (North Carolina) | 226.02 mi (363.74 km) |
| Harrisonburg to Southfield (Michigan) | 362.00 mi (582.58 km) |
| Harrisonburg to Southgate (Michigan) | 346.14 mi (557.05 km) |
| Harrisonburg to Southlake (Texas) | 1,090.93 mi (1,755.68 km) |
| Harrisonburg to Spanaway (Washington) | 2,256.96 mi (3,632.23 km) |
| Harrisonburg to Spanish Fork (Utah) | 1,746.53 mi (2,810.77 km) |
| Harrisonburg to Spanish Lake (Missouri) | 612.01 mi (984.93 km) |
| Harrisonburg to Spanish Springs (Nevada) | 2,171.76 mi (3,495.11 km) |
| Harrisonburg to Sparks (Nevada) | 2,175.31 mi (3,500.82 km) |
| Harrisonburg to Spartanburg (South Carolina) | 294.57 mi (474.07 km) |
| Harrisonburg to Spearfish (South Dakota) | 1,351.28 mi (2,174.67 km) |
| Harrisonburg to Speedway (Indiana) | 406.18 mi (653.68 km) |
| Harrisonburg to Spencer (Iowa) | 909.80 mi (1,464.19 km) |
| Harrisonburg to Spokane (Washington) | 2,024.72 mi (3,258.48 km) |
| Harrisonburg to Spokane Valley (Washington) | 2,015.49 mi (3,243.62 km) |
