| Gubbio to Southern Pines (North Carolina) | 4,695.86 mi (7,557.26 km) |
| Gubbio to Southfield (Michigan) | 4,549.91 mi (7,322.37 km) |
| Gubbio to Southgate (Michigan) | 4,559.15 mi (7,337.24 km) |
| Gubbio to Southlake (Texas) | 5,551.95 mi (8,934.99 km) |
| Gubbio to Spanaway (Washington) | 5,610.85 mi (9,029.79 km) |
| Gubbio to Spanish Fork (Utah) | 5,703.92 mi (9,179.57 km) |
| Gubbio to Spanish Lake (Missouri) | 4,992.68 mi (8,034.95 km) |
| Gubbio to Spanish Springs (Nevada) | 5,973.71 mi (9,613.75 km) |
| Gubbio to Sparks (Nevada) | 5,979.89 mi (9,623.70 km) |
| Gubbio to Spartanburg (South Carolina) | 4,817.63 mi (7,753.22 km) |
| Gubbio to Spearfish (South Dakota) | 5,215.81 mi (8,394.04 km) |
| Gubbio to Speedway (Indiana) | 4,787.10 mi (7,704.09 km) |
| Gubbio to Spencer (Iowa) | 4,979.10 mi (8,013.09 km) |
| Gubbio to Spokane (Washington) | 5,450.82 mi (8,772.24 km) |
| Gubbio to Spokane Valley (Washington) | 5,445.82 mi (8,764.21 km) |
